2020/9/30 – CRI Report

Investigation Report on China’s Botulinum Toxin Type A Market, 2020-2024

admin — Wed, 30 Sep 2020 05:20:01 +0000

Description
On Apr. 15, 2002, Botulinum Toxin Type A was approved by the FDA as a medical cosmetic that is injected to temporarily improve the appearance of moderate to severe glabellar lines. Later, some generic drugs appeared on the market. In addition to the imported Botulinum Toxin Type A (trade name: Botox) produced by Allergan, the Botulinum Toxin Type A products in China also include Botulinum Toxin Type A (trade name: Hengli) developed by Lanzhou Institute of Biological Products Co., Ltd.
According to CRI’s market research, Botulinum Toxin Type A has been growing rapidly since it entered China. From 2015 to 2019, its annual sales value increased from less than CNY104.88 million to CNY176.54 million, representing a CAGR of 13.9%.
In China, the medical use of Botulinum Toxin Type A is to treat adult blepharospasm and prosopospasm and some strabismuses, especially acute paralytic strabismus, concomitant strabismus, strabismus caused by endocrine diseases, and the strabismus that cannot be corrected surgically for those aged 12 and above. The incidence of facial neuropathy is increasing in China. Many people are attacked by prosopospasm when they are over-stressed or fatigued. Seeing global annual incidence of about 0.003%, facial neuropathy is more common in women than in men, and more common in middle-aged and elderly people than in people from other age groups.
However, more users of Botulinum Toxin Type A are women who pursue a thin face or less wrinkles. With more than 10 million cosmetic surgeries every year, the market size of medical beauty in China has exceeded USD 15 billion in 2019 and is still growing. As the demand for Botulinum Toxin Type A is expanding, some medical institutions and beauty salons have begun to inject Botulinum Toxin Type A smuggled from South Korea, France, Germany, etc. for their customers. Although the Chinese government only approved the sale of Botox and Hengli, smuggled Botulinum Toxin Type A products are easily available in China.
It is expected that, with the development of China’s economy, the rise of income, and the change of consumption habit, Chinese people will spend more in medical beauty, and the market size of Botulinum Toxin Type A will continue to grow in China in 2020-2024.

Topics Covered:
– Status of China’s medical beauty market
– Sales value and volume of Botulinum Toxin Type A in China 2015-2019
– Sales value and volume of Botulinum Toxin Type A in China by regions and manufacturers
-Prices of Botulinum Toxin Type A in China 2015-2019
– Competition on China’s Botulinum Toxin Type A market
– Major factors influencing the development of China’s Botulinum Toxin Type A market
– Prospect of China’s Botulinum Toxin Type A market from 2020 to 2024

The post Investigation Report on China’s Botulinum Toxin Type A Market, 2020-2024 first appeared on CRI Report.

Investigation Report on China Recombinant Factor Ⅷ (rFVIII) Market 2020-2024

admin — Wed, 30 Sep 2020 05:20:00 +0000

Description
There are approximately 400,000 to 1 million people with hemophilia in the world. Among them, there are about 100,000 to 200,000 patients in China. The registered hemophilia patients in China are less than 20,000, because most patients give up treatment due to the expensive medical expenses. Those who lack coagulation factor VIII account for 80% to 85% of the hemophilia A patients. Currently, there is no cure for hemophilia, treatment for which on the market are all alternatives. Coagulation factors are the main drugs.
In 1992, Baxter (Baxalta) publicized the first recombinant factor VIII(rFVIII). Because it has the same effects as natural coagulation factors without risks of blood-borne virus contamination, it is very popular in the market. The developed countries master mature technologies of recombinant coagulation factors. For example, recombinant coagulation factor VIII now has experienced four rounds of upgradation. The main manufacturers are Bayer, Baxalta, Pfizer, etc. By the end of 2020, no domestic recombinant coagulation factor VIII has been launched in China.
According to CRI’s market research, Recombinant Factor Ⅷ developed rapidly after entering China. Its annual sales increased from less than CNY 6 million in 2009 to CNY481 million in 2019, and the CAGR reached 55% in 2009 to 2019. Currently, Recombinant Factor Ⅷ sold on the Chinese market is all imported from Bayer, Baxalta and Pfizer. According to sales value, Bayer accounted for nearly 70% of the Chinese market in 2019.
CRI forecasts that with the development of China’s economy, patients with hemophilia are more able to pay medical expenses. It is expected that the market scale of Recombinant Factor Ⅷ in China will continue to increase from 2020 to 2024. After 2022, there is possibility that Chinese companies may launch Recombinant Factor Ⅷ.

Topics Covered:
-Development of Recombinant Factor Ⅷ in China
-Sales volume and value of Recombinant Factor Ⅷ in China
-Sales volume and value of Recombinant Factor Ⅷ in regions of China
-Price of Recombinant Factor Ⅷ in the Chinese market
-Key players of Recombinant Factor Ⅷ in the Chinese market
-Research progress of Chinese companies on Recombinant Factor Ⅷ
-Chinese market prospects on Recombinant Factor Ⅷ from 2020 to 2024

The post Investigation Report on China Recombinant Factor Ⅷ (rFVIII) Market 2020-2024 first appeared on CRI Report.

Investigation Report on China Entecavir Market 2020-2024

admin — Wed, 30 Sep 2020 05:19:59 +0000

Description
The number of people infected with hepatitis B virus (HBV) exceeds 100 million in China by the end of 2019, among which 20-30 million suffering from chronic Hepatitis B. About 0.5 million Chinese is estimated to die of liver damage and liver cancer caused by chronic Hepatitis B every year, causing a loss of over CNY100 billion for society.
Entecavir, a drug of oral deoxyguanosine, was developed by Bristol-Myers Squibb and approved to enter the market by FDA in Mar. 2005. Entecavir made by Sino-American Shanghai Squibb Pharmaceuticals Ltd got CFDA’s approval at the end of 2005 and entered the Chinese market in early 2006, followed by many generic drugs which promote market growth greatly.
According to CRI’s market research, the annual sales value of entecavir in China rose from CNY1126 million in 2013 to CNY 1996 million in 2017 and decreased to CNY1264 in 2019. Entecavir made by Sino-American Shanghai Squibb Pharmaceuticals Ltd dominates the Chinese market with a share of over 40% in 2019 by sales value.
Compared with the original nucleoside analogue, entecavir has stronger antiviral effects, faster onset, fewer side effects and lower resistance rate, thus inhibiting HBV strongly and having a high barrier to drug resistance. Entecavir makes it possible for patients to start with monotherapy which could be successful over a long term. As is known to all, new drug’s entering the anti-HBV drug market is bound to pose a threat to old ones, forming a new competitive landscape.
According to CRI, Due to the lack of new antiviral drugs for Hepatitis B in a long time, the market demand is far from being satisfied. Therefore, entecavir is estimated to enjoy good market prospects and its sales volume will keep growing in the next few years. However, due to the decline in average prices, sales of entecavir in the Chinese market may continue to decline.

Topic covered
-sales value and volume of entecavir in China 2015-2019
– sales value and volume of entecavir by dosages in China 2015-2019
-competitive landscape of entecavir in Chinese market
-price of entecavir by regions in China
-price of entecavir made by different manufacturers in China
-market outlook of entecavir in China

The post Investigation Report on China Entecavir Market 2020-2024 first appeared on CRI Report.

Investigation Report on China’s Ambroxol Market, 2020-2024

admin — Wed, 30 Sep 2020 05:19:59 +0000

Description
According to CRI, the incidence and case fatality rate of respiratory diseases in China are high in recent years. Following cardiovascular and cerebrovascular diseases and cancers, respiratory diseases rank third among the chronic diseases that cause deaths in China. Therefore, developing drugs for the treatment of respiratory diseases has become an important part of drug research. In the case of respiratory infections (respiratory diseases such as chronic bronchitis), a large amount of sputum is produced, which requires the application of expectorants. Respiratory mucus regulators are the main expectorants.
After years of development, third-generation expectorant ambroxol has become the most common drug in the clinical treatment of respiratory diseases. The chemical constituent of ambroxol is ambroxol hydrochloride, an active metabolite of Bromhexine. In 1981, ambroxol (trade name: Mucosolvan) developed by German company Boehringer Ingelheim was launched. Compared with the first and second generations of expectorants, ambroxol excels in dissolving mucus. In 1994, Boehringer Ingelheim’s ambroxol entered China. Afterwards, the generic drugs by Chinese companies also came onto the market.
According to CRI’s market research, ambroxol has been growing rapidly since it entered China. From 2005 to 2014, its annual sales value increased from less than CNY 200 million to CNY 1.26 billion, representing a CAGR of 20.9%. From 2015 to 2019, the sales revenue of ambroxol declined in China. By sales value, Boehringer Ingelheim takes up a market share of about 43.5% in the year of 2019. The rest market share is captured by Chinese companies, among which the top market players are Changzhou Siyao Pharmaceuticals Co., Ltd., Shenyang Xinma Pharmaceutical Co., Ltd., TIPR Pharmaceutical Responsible Co., Ltd. and Hainan Weikang Pharmaceutical (Qianshan) Co., Ltd. Ambroxol is sold in China in the dosage forms of injections, solutions, syrups, granules, tablets and capsules. Injections dominate the market.
Due to the outbreak of COVID-19 in 2020, the ability of Chinese hospitals to receive patients has declined. The decrease in the number of people seeking medical care makes China’s sales and sales of ambroxol show a downward trend in 2020. It is expected that the sales of ambroxol in China in 2020 will drop.
According to CRI, in 2021-2024, the Chinese ambroxol market will gradually recover. It is estimated that the sales of ambroxol in China will reach CNY929.41 million in 2024, and the CAGR will reach 6.0% in 2020-2024. It is estimated that the sales volume of ambroxol in China will reach 220.62 million in 2024, and the CAGR will reach 7.5% in 2020-2024.

Topics Covered:
– Situation of respiratory diseases in China
– Sales value and volume of China’s ambroxol 2015-2019
– Competitive landscape of China’s ambroxol market
– Prices of ambroxol in China
– Prices of ambroxol in China by regions and manufacturers
– Analysis on factors affecting the development of China’s ambroxol market
– Prospect of China’s ambroxol market from 2020 to 2024

The post Investigation Report on China’s Ambroxol Market, 2020-2024 first appeared on CRI Report.

Investigation Report on Chinese Recombinant Human Erythropoietin(rhEPO) Market, 2020-2024

admin — Wed, 30 Sep 2020 05:19:59 +0000

Description
There are approximately 400,000 to one million people with hemophilia in the world. Among them, there are about 100,000 to 200,000 patients in China. The registered hemophilia patients in China are less than 20,000, because most patients give up treatment due to the expensive medical expenses. Those who lack coagulation factor VIII account for 80% to 85% of the hemophilia A patients. Currently, there is no cure for hemophilia, treatment for which on the market are all alternatives. Coagulation factors are the main drugs.
In 1992, Baxter (Baxalta) publicized the first recombinant factor VIII(rFVIII). Because it has the same effects as natural coagulation factors without risks of blood-borne virus contamination, it is very popular in the market. The developed countries master mature technologies of recombinant coagulation factors. For example, recombinant coagulation factor VIII now has experienced four rounds of upgradation. The main manufacturers are Bayer, Baxalta, Pfizer, etc. By the end of 2020, no domestic recombinant coagulation factor VIII has been launched in China.
According to CRI’s market research, Recombinant Factor Ⅷ developed rapidly after entering China. Its annual sales increased from less than CNY 6 million in 2009 to CNY481 million in 2019, and the CAGR reached 55% in 2009 to 2019. Currently, Recombinant Factor Ⅷ sold on the Chinese market is all imported from Bayer, Baxalta and Pfizer. According to sales value, Bayer accounted for nearly 70% of the Chinese market in 2019.
CRI forecasts that with the development of China’s economy, patients with hemophilia are more able to pay medical expenses. It is expected that the market scale of Recombinant Factor Ⅷ in China will continue to increase from 2020 to 2024. After 2022, there is possibility that Chinese companies may launch Recombinant Factor Ⅷ.

The post Investigation Report on Chinese Recombinant Human Erythropoietin(rhEPO) Market, 2020-2024 first appeared on CRI Report.