2018/11/14 – CRI Report

Investigation Report on China’s Metoprolol Market, 2018-2022

admin — Thu, 15 Nov 2018 02:04:07 +0000

Description
Estimated according to the population size and structure, there are about 330 million hypertensive patients in China, which means that one in every three adults suffers from hypertension. Chinese hypertensive patients in China account for about one-third of the global total. The incidence of hypertension in China rose from 5.1% in 1959 to 37.2% in 2017 by 32.1%. With so many hypertensive patients, China’s antihypertensive drug market is growing steadily.
There are various antihypertensive drugs in China, which leads to fierce competition. As first-line antihypertensive drugs in China, β-blockers represented by Metoprolol, Bisoprolol, Perindopril and benazepril have a stable market share. Metoprolol is a selective β1 receptor blocker that treats cardiovascular diseases, especially hypertension, angina and tachycardia. The Metoprolol Tartrate preparations approved to be marketed in China include tablets, capsules, sustained-release tablets, controlled-release tablets and injections. AstraZeneca’s proprietary drug is sold in the trade name of Betaloc. In addition, generic Metoprolol produced by over 10 manufacturers are also sold in China. According to CRI’s market research, the market size of Metoprolol in China was about CNY 492 million in 2017, of which AstraZeneca accounted for more than 90%. The top Chinese companies included Guangzhou Baiyunshan Tianxin Pharmaceutical Co., Ltd., Shanghai Sine Promod Pharmaceutical Co., Ltd. and Zhuhai Tongyuan Pharmaceutical Co., Ltd.
As the number of hypertensive patients is growing with the rapidly aging population, and generic β-blockers are popularized, it is expected that Metoprolol will still have some growth potential in China.

Topics Covered:
– Situation of hypertension in China
– Sales of Metoprolol in China
– Major Metoprolol manufacturers in China
– Competition on China’s Metoprolol market
– Driving forces and opportunities for China’s Metoprolol market
– Forecasts on China’s Metoprolol market from 2018 to 2022

The post Investigation Report on China’s Metoprolol Market, 2018-2022 first appeared on CRI Report.

Investigation Report on China’s Metformin Market, 2018-2022

admin — Thu, 15 Nov 2018 02:04:06 +0000

Description
The rapid development of the Chinese economy in the past three decades has changed people’s dietary habits and reduced physical activities, which leads to an increasing incidence of obesity-related diseases. It is estimated that at the end of 2017, there were more than 100 million diabetic patients in China. Most of them were type 2 diabetic patients.
As a first-line drug for type 2 diabetes, Metformin can prevent microangiopathy and macroangiopathy caused by diabetes, relieve hyperinsulinemia and insulin resistance, improve blood lipid metabolism, and reverse pre-diabetes.
Metformin was discovered as early as 1929. But it was ignored due to the prevalence of insulin. It was not until 1995 that Metformin was approved to be marketed in the U.S. Effective and inexpensive, Metformin has become the first-line recommendation for the treatment of various diabetes. For example, the Guidelines for the Prevention and Treatment of Type 2 Diabetes in China (2017 Edition) says, “The drug of first choice for treating type 2 diabetes is Metformin.”
The sales value of Metformin has been growing since Metformin entered China in 1999. According to CRI’s market research, in 2017, the sales value of Metformin in China was about CNY 572 million. By sales value, Sino-American Shanghai Squibb Pharmaceuticals Ltd. and its parent company BMS took up about 76% market share, and the rest market share was captured by Chongqing Conquer Pharmaceutical Co., Ltd., Beijing Liling Hengtai Pharmaceutical Co., Ltd., Beijing Shengyong Pharmaceutical Co., Ltd., etc.
In addition to treating diabetes, Metformin can be used as a conventional treatment of polycystic ovary syndrome in clinical practice. Insulin is a growth hormone. Many studies have found that there is a much higher risk of cancer among type 2 diabetic patients. Although the mechanism is unknown, Metformin can reduce the risk of cancer for diabetic patients, and it may be used to prevent and treat cancer in the future. Some studies have even found that Metformin can potentially relieve the symptoms of non-alcoholic fatty liver disease, prevent and treat uveitis, a common blinding disease, and reduce the incidence of Parkinson’s disease.
It is expected that as the incidence of diabetes and the number of diabetic patients continue to rise in China, and Metformin is applied in more fields, the market size of Metformin will continue to grow in China in the next few years.

Topics Covered:
– Incidence of type 2 diabetes in China
– Size of China’s Metformin market
– Competition on China’s Metformin market
– Retail prices of Metformin in China
– Prospect of China’s Metformin market

The post Investigation Report on China’s Metformin Market, 2018-2022 first appeared on CRI Report.

Investigation Report on China’s Ambroxol Market, 2018-2022

admin — Thu, 15 Nov 2018 02:04:03 +0000

According to CRI, the incidence and case fatality rate of respiratory diseases in China are high in recent years. Following cardiovascular and cerebrovascular diseases and cancers, respiratory diseases rank third among the chronic diseases that cause deaths in China. Therefore, developing drugs for the treatment of respiratory diseases has become an important part of drug research. In the case of respiratory infections (respiratory diseases such as chronic bronchitis), a large amount of sputum is produced, which requires the application of expectorants. Respiratory mucus regulators are the main expectorants.
After years of development, third-generation expectorant Ambroxol has become the most common drug in the clinical treatment of respiratory diseases. The chemical constituent of Ambroxol is ambroxol hydrochloride, an active metabolite of Bromhexine. In 1981, Ambroxol (trade name: Mucosolvan) developed by German company Boehringer Ingelheim was launched. Compared with the first and second generations of expectorants, Ambroxol excels in dissolving mucus. In 1994, Boehringer Ingelheim’s Ambroxol entered China. Afterwards, the generic drugs by Chinese companies also came onto the market.
According to CRI’s market research, Ambroxol has been growing rapidly since it entered China. From 2005 to 2014, its annual sales value increased from less than CNY 200 million to CNY 1.26 billion, representing a CAGR of 20.9%. From 2015 to 2017, the sales revenue of Ambroxol declined in China. By sales value, Boehringer Ingelheim takes up a market share of about 44%. The rest market share is captured by Chinese companies, among which the top market players are Changzhou Siyao Pharmaceuticals Co., Ltd., Shenyang Xinma Pharmaceutical Co., Ltd., TIPR Pharmaceutical Responsible Co., Ltd. and Hainan Weikang Pharmaceutical (Qianshan) Co., Ltd. Ambroxol is sold in China in the dosage forms of injections, solutions, syrups, granules, tablets and capsules. Injections dominate the market.
As environmental pollution and population aging intensify, the incidence of respiratory diseases will keep rising, it is expected that Ambroxol will still have some growth potential in China in the next few years.

Topics Covered:
– Situation of respiratory diseases in China
– Size of China’s Ambroxol market
– Competitive landscape of China’s Ambroxol market
– Prices of Ambroxol in China
– Analysis on factors affecting the development of China’s Ambroxol market
– Prospect of China’s Ambroxol market from 2018 to 2022

The post Investigation Report on China’s Ambroxol Market, 2018-2022 first appeared on CRI Report.