Investigation Report on China’s Aflibercept Market 2022-2031

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According to CRI’s market research, after Aflibercept entered the Chinese market, the sales value of Aflibercept in China increased from CNY8.3 million in 2018 to CNY238 million in 2021.

Description

Aflibercept is an anti-VEGF drug, mainly used to treat neovascular age-related macular degeneration (wAMD), and other retinopathy caused by visual impairment. Aflibercept was jointly developed by Regeneron and Bayer. Regeneron has exclusive sales rights in the U.S. market, while Bayer obtains exclusive sales rights outside the U.S. Their Aflibercept, EYLEA was launched in China in 2018. By July 2022, Bayer AG is the only manufacturer in the Chinese Aflibercept market.

According to CRI’s market research, after Aflibercept entered the Chinese market, the sales value of Aflibercept in China increased from CNY8.3 million in 2018 to CNY238 million in 2021. The annual growth rate in 2021 was 116%, which slowed down due to the COVID-19 epidemic. The CAGR of sales value of aflibercept in China is 206% from 2018 to 2021.

CRI analyzes that as the epidemic situation has been improved and the hospitals resume their operation, the sales of Aflibercept will have a recovery growth from 2023 to 2026. In addition, the sales will also increase due to market expansion. Currently, China has only approved two indications for Aflibercept, including treatment of wAMD and treatment of DME. However, Aflibercept had five approved indications globally, which means the sales will continue to grow as the number of indications expands. On the other hand, though the anti-VEGF ophthalmic drug market where Aflibercept belongs to accounts for the largest market share in the ophthalmology drug industry, the penetration rate for the anti-VEGF drug is still low. The penetration rate for the anti-VEGF drug is about 1% in China, while it exceeds 5% in the U.S. Since the market demand has not yet reached saturation, the sales will keep increasing. Besides, Aflibercept was included in the national medical insurance catalog at the beginning of 2020, so the price has been lowered, which reduces the burden on patients and will stimulate sales in the future.

Qilu Pharmaceutical, a local Chinese pharmaceutical company, received CDE (CENTER FOR DRUG EVALUATION, NMPA) approval for its marketing authorization application for aflibercept intravitreal injection in April 2022, which is the first biosimilar application for aflibercept in China.

According to CRI’s market research, a number of other pharmaceutical companies in China are in the process of genericizing aflibercept, such as Clover Biopharmaceuticals’ aflibercept intraocular injection, which is in the clinical phase of application, and Shandong Boan Biotechnology Co.

It is expected that the generic version of aflibercept will enter the Chinese market in the next five years, but it is unlikely to have a significant impact on Bayer’s original drug in the short term.

 

Topics Covered:

  • The impact of COVID-19 on China’s aflibercept market
  • Sales value and volume of China’s aflibercept 2016-2020
  • Competitive landscape of China’s aflibercept market
  • Prices of aflibercept in China
  • Prices of aflibercept in China by regions and manufacturers
  • Analysis on factors affecting the development of China’s aflibercept market
  • Prospect of China’s aflibercept market from 2021 to 2025

Additional information

Publisher

Geography Covered

Date Published

Pages

Charts

Format

Base Year

2022

Base Market Size

285.77

Currency

CNY million

Forecast Year

2031

Market Size Forecast

3162.04

CAGR

30.62%

Table of Contents

1 Relevant Concepts of Aflibercept     

1.1 Indications for Aflibercept     

1.2 Development of Aflibercept in China    

1.3 Governmental Approval of Aflibercept in China

1.4 The Impact of COVID-19 on Aflibercept sales in China

 

2 Sales of Aflibercept in China, 2018-2021

2.1 Sales Value of Aflibercept

2.1.1 Overall Sales Value

2.1.2 Sales Value by Region 

2.2 Sales Volume of Aflibercept   

2.2.1 Overall Sales Volume  

2.2.2 Sales Volume by Region     

2.3 Sales of Aflibercept by Dosage Form in China, 2018-2021  

2.3.1 Intraocular Injection

2.3.2 Analysis of Other Dosage Forms

      

3 Analysis of Major Aflibercept Manufacturers in China, 2018-2021

3.1 Analysis of Market Share of Major Aflibercept Manufacturers    

3.1.1 Investigation on Market Share by Sales Value    

3.1.2 Investigation on Market Share by Sales volume 

3.2 Bayer AG

3.2.1 Enterprise Profile 

3.2.2 Sales of EYLEA (Bayer’s Aflibercept) in China 

 

4 Prices of Aflibercept for Different Manufacturers in China, 2021-2022

4.1 Bayer AG (EYLEA)

4.2 Others

 

5 Prospect of Chinese Aflibercept drug Market, 2022-2031

5.1 Influential Factors of Chinese Aflibercept Market Development

5.1.1 The Impact of COVID-19 on Chinese Aflibercept Market

5.1.2 Market Drivers and Opportunities

5.1.3 Market Threats and Challenges

5.2 Forecast on Market Size 

5.3 Forecast on Market Trend

 

List of Charts

Chart Aflibercept Drugs Approved by Chinese Government, by 2022

Chart Sales Value of Aflibercept in China, 2018-2021 

Chart Sales Value of Aflibercept in Regions of China, 2018-2021 (Unit: CNY thousand)

Chart Sales Volume of Aflibercept in China, 2018-2021     

Chart Sales Volume of Aflibercept in Regions of China,2018-2021   

Chart Sales value and volume of aflibercept intravitreal injection in China 2018-2021     

Chart Market Share of Aflibercept Manufacturers by Sales Value in China, 2018-2021    

Chart Market Share of Aflibercept Manufacturers by Sales Volume in China, 2018-2021

Chart Profile of Bayer AG    

Chart Sales Value of Bayer AG’s Aflibercept in China, 2018-2021    

Chart Sales Volume of Bayer AG ‘s Aflibercept in China, 2018-2021 

Chart EYLEA sold in the Chinese market    

Chart Prices of BAYER AG’s Aflibercept (EYLEA ®) in Parts of China, 2021 

Chart Forecast on sales of aflibercept in China 2022-2026 

Companies Mentioned

Bayer AG (EYLEA)

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